Accessibility - Best Practice: Design

Whitespace (or negative space) is just as important as the content itself, as it helps to improve readability, navigation, and the overall visual appeal of your design.
Ensure spacing is consistent in your design, such as margins, padding, and line spacing - this helps to create a balanced design and makes content easier to digest.
Ensure each piece of interactivity is spaced far enough apart to avoid accidental clicks.
Position content in a way that aligns with natural reading patterns - most users read left to right and top to bottom, so place key your content accordingly.
Place important call-to-action buttons toward the centre or bottom of the page to catch users’ attention as they reach the end of a section.
Consider using a menu to help users navigate.
Avoid using too many colours, and ensure there is enough contrast between text and background colour.
Don’t rely on colour alone to convey important information, as people with colour blindness may not perceive the colours as intended.
Avoid using very bright or clashing colours, as they can cause eye strain or be difficult to read, especially those with visual impairments or sensitive to bright light.

WebAIM Contrast Checker is a popular tool for evaluating the colour contrast ratio between two colours.

Create a document design that's usable and accessible for all users